Introducing his 2004 film The Libertine, about a 17th-century poet who notoriously drank himself to an early death, the 54-year-old chose to discuss American politics.
“I think [Donald] Trump needs help,” he said. “There are a lot of dark places he could go.”
He added: “I’m not insinuating anything – by the way this will be in the press and it will be horrible – but when was the last time an actor assassinated a president?”
Depp then added, “I want to clarify, I am not an actor. I lie for a living. However, it has been a while, and maybe it is time.”